romidepsin FDA Link

a bicyclic depsipeptide and a potent histone deacetylase inhibitor from Chromobacterium violaceum; structure in first source

Also Known As:

FK228; FR901228; FR 901228; FR-901228; L-Valine, N- (3- hydroxy- 7- mercapto- 1- oxo- 4- heptenyl)- D- valyl- D- cysteinyl- (Z)- 2,3- didehydro- 2- aminobutanoyl- , xi-lactone, cyclic (1-2)-disulfide, (S-(E))-; istodax

Pharmalogical Action Categories:

D000903 - Antibiotics, Antineoplastic

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - Depsipeptides: 297
      - romidepsin: 505
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - Depsipeptides: 297
      - romidepsin: 505

A R Robbins Selected Research

A R Robbins Research Topics

Disease

Drug/Important Bio-Agent (IBA)